Adenosine deaminase deficiency and severe combined immunodeficiency disease.
نویسندگان
چکیده
The nature of the association of adenosine deaminase deficiency and severe combined immunodeficiency disease is reviewed . The basis for the molecular heterogeneity exhibited by adenosine deaminase in human tissue and the mechanisms whereby a deficiency of this activity results in the extreme perturbation of the immune system as observed in severe combined immunodeficiency are critically discussed.
منابع مشابه
Chronic Inflammatory Demyelinating Polyneuropathy in a Patient with Adenosine Deaminase Deficiency Severe Combined Immunodeficiency: Case Report
Adenosine deaminase deficiency is a type of severe combined immunodeficiency that involves about 15% of all SCID cases. This form of SCID has low B cells, T cells, and NK cells. This condition is complex with many possible complications including neurological abnormalities. Guillainbarré syndrome is an acute inflammatory disease of the peripheral nerves that involves an autoimmune attack on mye...
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ورودعنوان ژورنال:
- Advances in enzymology and related areas of molecular biology
دوره 51 شماره
صفحات -
تاریخ انتشار 1977